ABOUT US

Connecting Kyoto to the World

About Xeno-Interface Inc.

Xeno-Interface Inc. was founded as a company to challenge what is impossible in nature in the field of fusion (Xeno means artificial and Interface means the overlapping part of two theories or phenomena).
Currently, we are developing our drug discovery platform technology business and drug discovery business in the field of mid-molecular drug discovery, which combines the characteristics of both small molecules and macromolecules. With our unique drug discovery platform technology, we are challenging to develop therapeutics for diseases for which there are no satisfactory treatments.

The Future of Drug Discovery Challenged by Teams

Developing novel drug discovery technologies through collaboration with diverse partners

Introduction of Founders and Advisors

MEMBER

Founder and CEO

Kazuhiro Hayashi

Born in Yamaguchi prefecture, 1982
CEO, Xeno-Interface Inc.

Graduated from Kyoto University, Faculty of Pharmaceutical Sciences, Department of General Pharmaceutical Sciences.
PhD. in Pharmaceutical Sciences from the Graduate School of Pharmaceutical Sciences, Kyoto University, Japan, and has been a JSPS Postdoctoral Fellow at Harvard University since 2011. JSPS Research Associate at Harvard University. After becoming a Research Associate at Harvard University, he started his own project at the Graduate School of Medicine, Graduate School of Life Sciences, and Institute for Chemical Research, Kyoto University, where he has been in his current position since 2019. He specializes in peptide and genetic medicines, developing novel drug discovery technologies that use molecular design as the key to effective treatment of the causes of difficult-to-treat diseases.

− Other Biographies

・Research Fellow of the Japan Society for the Promotion of Science (DC1)
         
・Otsu Conference 1st Member
         
・山Yamada Science Foundation Long-term dispatch assistance
          
・Uehara Memorial Life Science Foundation Postdoctoral Fellowship
         
・JSPS Postdoctoral Fellowship for Research Abroad

− Patent

2013.9
International Patent (PCT) Filing
Name of invention: Proline-locked stapled peptides and uses thereof
Application date: 2013.9.26
Application Number: PCT/US2013/062004
Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Inventor: Gregory L. Verdine、Kazuhiro Hayashi
               

− Others

2022
Advance to the finals of the Health and Medical Venture Award
       
   

Advisor

Strategic Advisor

Yasuhiro Ono

Specialist in technology investment. D. (Engineering, University of Tokyo). He has over 20 years of experience in a wide range of strategic investment and business development activities in North America, Asia, and Japan for Mitsubishi Corporation, major financial institutions, and one of the world's largest infrastructure funds, where he led strategy planning and investment execution for infrastructure technology investments totaling over 1 trillion yen. During that time, he studied at Harvard University Graduate School of Engineering, where he received his M.S., and at the University of Tokyo, where he received his Ph. His research interests include mathematical model analysis of carbon dioxide absorption by forests from the perspective of renewable energy and carbon management, and demonstration of aircraft fuel production using fast-growing trees.

Sole author: Analysis of Disincentive for Introduction of Forest Investment Funds in Japan, Journal of Forestry Economics, 2017, Vol. 63, No. 2, p32-40
Sole author: Prospects for Forest Investment Funds - Through Comparison with Real Estate Investment and Infrastructure Investment, Forestry Economics, 2017, Vol. 70, No. 5, p32-40
Co-author: Forest Future Conference - Creating a Mechanism to Utilize Forests - Minoru Kumazaki, Toru Hayami, Ryoko Ishizaki [editors], ISBN978-4-8067-1583-2, published June 2019

Collaborative Research Members

                           

Collaborative Researchers

Michiyuki Matsuda

Specialties: Pathology, Cell biology, Bioimaging

Education Graduated from the University of Tokyo, Faculty of Medicine, Showa 58, Japan.
Graduate School of Medicine, University of Tokyo, Doctoral Course, Showa 62
Doctor of Medicine March 30, 1962 (Instructor: Prof. Morikatsu)
Qualified as a physician, exempted from license, Showa 58
Qualification in dead body dissection, Showa 62
Accredited by the Japanese Society of Pathology, Showa 63.

Career Summary Director, Office of Research, Department of Pathology, National Institute of Health, 1987-1996
Research Associate, Rockefeller University 1988-1992
Researcher, New Technology Development Corporation of Japan (PRESTO 21) 1992-1996
Director, Division of Clinical Pathology Research, National Institute for Global Health and Medicine 1996-1992
Professor, Division of Tumor Virus, Research Institute for Microbial Diseases, Osaka University 2001 - 2006
Professor, Department of Pathobiomedical Sciences, Graduate School of Medicine, Kyoto University April 2006 - Present
Professor, Department of Biological Control, Graduate School of Life Sciences, Kyoto University April 2007-Present
Member of Science Council of Japan (24th and 25th terms) October, 2009 - Present
Director, Center for Biodynamics Research, Graduate School of Life Sciences, Kyoto University, April 2008-Present
Director, CREST “Multicellular” Area, Japan Science and Technology Agency, June 2048-Present
Chairman, Committee on Basic Medicine, Science Council of Japan October 2020-Present

Award 1994 Sugiura Incentive Award of the Japanese Society of Virology
1997 Japanese Cancer Association Encouragement Award
November 25, 2008 The 6th Sagawa Special Research Grant Award
October 28, 2011 2011 Mochida Memorial Academic Award
February 16, 2008 Grand Prize, Nakatani Award 2009
May 10, 2048 Japan Pathology Prize

                     

Collaborative Researchers

Kosuke Fujishima

Kosuke Fujishima was born in Tokyo in 1982.
Associate Professor at the Earth-Life Science Institute (ELSI), Tokyo Institute of Technology,
and Associate Professor at the Graduate School of Media and Governance, Keio University.

After graduating from the Faculty of Environment and Information Studies at Keio University in 2005, he completed his doctoral studies at the Graduate School of Media and Governance in 2009. After working as a JSPS Postdoctoral Fellow abroad, a researcher at NASA Ames Research Center, and an ELSI researcher, he has been in his current position since September 2020.

He is engaged in research on the origin of life using synthetic biology and protein evolution in vitro. In the past, he has appeared on TV programs such as Cosmic Front (NHK BS Premium), Naoki Matayoshi's Heureka! (NHK E-television).

Collaborative Researchers

Naoki Suzuki

Department of Neurology, Tohoku University Hospital

                       

https://researchmap.jp/NaokiSuzuki

− Patents

2021.10
International Patent (PCT) Application Completed
Title of invention: β-strand bridge peptides
Filing date: October 29, 2021
Application Number: PCT/JP2021/040138
Applicant: Xeno-Interface Inc., Kyoto University
Inventors: Kazuhiro Hayashi, Michiyuki Matsuda